A suicide bombing has killed at least 95 people and injured 158 others in the centre of Afghanistan's capital, Kabul, officials say.
Attackers drove an ambulance laden with explosives past a police checkpoint into a street that was only open to government workers.
It happened near the old interior ministry building and offices of the European Union and High Peace Council.
The Taliban have said they carried out the attack, the deadliest for months.
A week ago, Taliban militants killed 22 people in a luxury Kabul hotel.
Witnesses say the area - home to foreign embassies, the city's police headquarters and a shopping zone known as Chicken Street - was crowded with people when the bomb exploded on Saturday at about 12:15 local time (08:45 GMT).
He was having lunch at his family home, just metres away, when the blast went off. "First of all we thought it was inside our house," he said. Then he went outside and saw scattered bodies. "It is very, very inhumane."
Another witness, a software engineer who wished to remain anonymous, told the BBC he was about a 1km away when he heard the noise.
"I saw a huge flame," he said. "The smoke was pungent. It entered my eyes and I was not able to see for some time."
He said when he moved closer he saw the dead bodies, and it looked like a "brutal graveyard". "It was a terrible moment. [The area] is completely destroyed."
The International Committee of the Red Cross said the use of an ambulance was "harrowing".
Nasrat Rahimi, deputy spokesperson for the Interior Ministry, said the attacker got through a security checkpoint after telling police he was taking a patient to nearby Jamhuriat hospital.
He detonated the bomb at a second checkpoint, said Mr Rahimi.
The BBC's Zia Shahreyar, speaking from the scene, says it is not easy to get through the checkpoints. Cars are searched and drivers' identities checked.
He adds that questions will be asked about how the attacker got through.
This is the deadliest attack in Kabul in several months.
In October, 176 people were killed in bomb attacks across Afghanistan in one week. The country's security forces in particular have suffered heavy casualties at the hands of the Taliban, who want to re-impose their strict version of Islamic law in the country.
In May, 150 people were killed by a suicide bomb attack in Kabul. The Taliban denied any role, but the Afghan government says its affiliate, the Haqqani group, carried it out with support from Pakistan.
Pakistan denies supporting militants that carry out attacks in Afghanistan. This month, the US cut its security aid to Pakistan, saying it had failed to take action against terrorist networks on its soil.
Image copyrightAFPImage captionMore than 150 people were wounded in the bombingImage copyrightEPAImage captionThe area of the attack was a scene of devastation
The Taliban control large swathes of Afghanistan and parts of neighbouring Pakistan.
They were ousted from power in Afghanistan after a US-led invasion in 2001 but returned to run some key areas.
Who are the Taliban?
The hardline Islamic Taliban movement swept to power in Afghanistan in 1996 after the civil war which followed the Soviet-Afghan war, and were ousted by the US-led invasion five years later
In power, they imposed a brutal version of Sharia law, such as public executions and amputations, and banned women from public life
Men had to grow beards and women to wear the all-covering burka; television, music and cinema were banned
They sheltered al-Qaeda leaders before and after being ousted - since then they have fought a bloody insurgency which continues today
Image copyrightBBC AFGHANImage captionA plume of smoke from the explosion was seen around the cityImage copyrightWAKIL KOHSARImage captionKabul hospitals were overwhelmed with patients in the aftermath
Keep these in mind as you contemplate the direction of the American government over the past 50 years and especially since the Obama election.
The Goals of Communism
(as read into the congressional record January 10, 1963, from "The Naked Communist" by Cleon Skousen)
1. U.S. acceptance of coexistence as the only alternative to atomic war.
2. U.S. willingness to capitulate in preference to engaging in atomic war.
3. Develop the illusion that total disarmament of the United States would be a demonstration of moral strength.
4. Permit free trade between all nations regardless of Communist affiliation and regardless of whether or not items could be used for war.
5. Extension of long-term loans to Russia and Soviet satellites.
6. Provide American aid to all nations regardless of Communist domination.
7. Grant recognition of Red China. Admission of Red China to the U.N.
8. Set up East and West Germany as separate states in spite of Khrushchev's promise in 1955 to settle the German question by free elections under supervision of the U.N.
9. Prolong the conferences to ban atomic tests because the United States has agreed to suspend tests as long as negotiations are in progress.
10. Allow all Soviet satellites individual representation in the U.N.
11. Promote the U.N. as the only hope for mankind. If its charter is rewritten, demand that it be set up as a one-world government with its own independent armed forces. (Some Communist leaders believe the world can be taken over as easily by the U.N. as by Moscow. Sometimes these two centers compete with each other as they are now doing in the Congo.)
12. Resist any attempt to outlaw the Communist Party.
13. Do away with all loyalty oaths.
14. Continue giving Russia access to the U.S. Patent Office.
15. Capture one or both of the political parties in the United States.
16. Use technical decisions of the courts to weaken basic American institutions by claiming their activities violate civil rights.
17. Get control of the schools. Use them as transmission belts for socialism and current Communist propaganda. Soften the curriculum. Get control of teachers' associations. Put the party line in textbooks.
18. Gain control of all student newspapers.
19. Use student riots to foment public protests against programs or organizations which are under Communist attack.
20. Infiltrate the press. Get control of book-review assignments, editorial writing, policymaking positions.
21. Gain control of key positions in radio, TV, and motion pictures.
22. Continue discrediting American culture by degrading all forms of artistic expression. An American Communist cell was told to "eliminate all good sculpture from parks and buildings, substitute shapeless, awkward and meaningless forms."
23. Control art critics and directors of art museums. "Our plan is to promote ugliness, repulsive, meaningless art."
24. Eliminate all laws governing obscenity by calling them "censorship" and a violation of free speech and free press.
25. Break down cultural standards of morality by promoting pornography and obscenity in books, magazines, motion pictures, radio, and TV.
26. Present homosexuality, degeneracy and promiscuity as "normal, natural, healthy."
27. Infiltrate the churches and replace revealed religion with "social" religion. Discredit the Bible and emphasize the need for intellectual maturity which does not need a "religious crutch."
28. Eliminate prayer or any phase of religious expression in the schools on the ground that it violates the principle of "separation of church and state."
29. Discredit the American Constitution by calling it inadequate, old-fashioned, out of step with modern needs, a hindrance to cooperation between nations on a worldwide basis.
30. Discredit the American Founding Fathers. Present them as selfish aristocrats who had no concern for the "common man."
31. Belittle all forms of American culture and discourage the teaching of American history on the ground that it was only a minor part of the "big picture." Give more emphasis to Russian history since the Communists took over.
32. Support any socialist movement to give centralized control over any part of the culture--education, social agencies, welfare programs, mental health clinics, etc.
33. Eliminate all laws or procedures which interfere with the operation of the Communist apparatus.
34. Eliminate the House Committee on Un-American Activities.
35. Discredit and eventually dismantle the FBI.
36. Infiltrate and gain control of more unions.
37. Infiltrate and gain control of big business.
38. Transfer some of the powers of arrest from the police to social agencies. Treat all behavioral problems as psychiatric disorders which no one but psychiatrists can understand.
39. Dominate the psychiatric profession and use mental health laws as a means of gaining coercive control over those who oppose Communist goals.
40. Discredit the family as an institution. Encourage promiscuity and easy divorce.
41. Emphasize the need to raise children away from the negative influence of parents. Attribute prejudices, mental blocks and retarding of children to suppressive influence of parents.
42. Create the impression that violence and insurrection are legitimate aspects of the American tradition; that students and special-interest groups should rise up and use united force to solve economic, political or social problems.
43. Overthrow all colonial governments before native populations are ready for self-government.
44. Internationalize the Panama Canal.
45. Repeal the Connally reservation so the United States cannot prevent the World Court from seizing jurisdiction over nations and individuals alike.
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